The role of NK1.1S+ cells and TH1 cytokines in the pathogenesis of acute murine graft-versus-host disease (GVHD)
Previous studies using a murine F1-hybrid model of acute GVHD have shown that mortality is prevented if the graft is depleted of NK1.1 + cells. The precise role played by these cells in the pathogenesis of GVHD has not been elucidated, but it is thought that they injure host target tissues. Two cyt...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/1780 |