Functional analysis on the interactions of the human immunodeficiency virus type 1 integrase with its cofactors that regulate viral replication

Like all viruses, the replication of HIV-1 relies heavily on host proteins due to its limited genome products. HIV-1 integrase (IN) catalyzes the integration of viral DNA into host genome and also impacts other steps of viral replication cycle, all of which are assisted by various cellular proteins....

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Bibliographic Details
Main Author: Zheng, Yingfeng
Other Authors: Yao, Xiaojian (Medical Microbiology)
Published: BioMed Central Ltd 2013
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Online Access:http://hdl.handle.net/1993/16248