Method Development for the Assignment of NMR Peaks and the Determination of Quaternary Protein Structure using Reductive Methylation
The work described herein is centered on reductive methylation, a chemical modification reaction, which allows for the introduction of methyl groups at the primary amines of the lysine side chain and at the N-terminus. The resulting methyl groups are effective probes for the study of protein structu...
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Format: | Others |
Language: | en |
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LSU
2015
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Online Access: | http://etd.lsu.edu/docs/available/etd-11162015-102349/ |