Method Development for the Assignment of NMR Peaks and the Determination of Quaternary Protein Structure using Reductive Methylation

The work described herein is centered on reductive methylation, a chemical modification reaction, which allows for the introduction of methyl groups at the primary amines of the lysine side chain and at the N-terminus. The resulting methyl groups are effective probes for the study of protein structu...

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Bibliographic Details
Main Author: Brady, Pamlea Nicole
Other Authors: Macnaughtan, Megan A.
Format: Others
Language:en
Published: LSU 2015
Subjects:
Online Access:http://etd.lsu.edu/docs/available/etd-11162015-102349/