Depolarization by Transient Receptor Potential Melastatin 4 in Pancreatic Alpha-Cells Regulates Glucagon Secretion

The Transient Receptor Potential Melastatin 4 protein (TRPM4) is a member of the TRP family of ion channels that is expressed in both electrically excitable and non-excitable cells. Functional studies revealed that TRPM4 significantly impacts Ca2+ signals in both immune and pancreatic β-cells, which...

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Bibliographic Details
Main Author: Nelson, Piper Lynn
Other Authors: Yoshimura, Masami
Format: Others
Language:en
Published: LSU 2010
Subjects:
Online Access:http://etd.lsu.edu/docs/available/etd-11152010-155245/