Thermodynamics of DNA Binding and Break Repair by the Pol I DNA Polymerases from Escherichia coli and Thermus aquaticus
Klenow and Klentaq are the large fragments of the Pol I DNA polymerases from Escherichia coli and Thermus aquaticus. Examination of the DNA binding thermodynamics of both polymerases to replication versus repair substrates shows that Klenow binds primed-template DNA with up to 50X higher affinity th...
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| Format: | Others |
| Language: | en |
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LSU
2011
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| Online Access: | http://etd.lsu.edu/docs/available/etd-08042011-230059/ |