Attachment of Oligonucleotide Probes to Polymer Biochips and Its Application for the Detection of Point Mutations

This dissertation is on the fabrication of polymer-based microfluidic arrays for the detection of genetic mutations. Poly(methyl methacrylate) was chosen as one of the polymer substrate materials due to its low background noise, low adsorption of biomolecules, and low assembly temperature. The surfa...

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Bibliographic Details
Main Author: Wang, Yun
Other Authors: Steven A. Soper
Format: Others
Language:en
Published: LSU 2004
Subjects:
Online Access:http://etd.lsu.edu/docs/available/etd-01072004-084210/