Over-expression of the potassium-chloride co-transporter KCC2 in developing zebrafish

In embryonic neurons, the intracellular chloride concentration is elevated, making GABA and glycine depolarizing. Later in development, coincident with neuronal maturation, the extruding potassium-chloride co-transporter KCC2 is expressed. It reverses the chloride gradient, rendering it hyperpolariz...

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Bibliographic Details
Main Author: Reynolds, Annie, 1978-
Format: Others
Language:en
Published: McGill University 2006
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98778