Over-expression of the potassium-chloride co-transporter KCC2 in developing zebrafish
In embryonic neurons, the intracellular chloride concentration is elevated, making GABA and glycine depolarizing. Later in development, coincident with neuronal maturation, the extruding potassium-chloride co-transporter KCC2 is expressed. It reverses the chloride gradient, rendering it hyperpolariz...
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Format: | Others |
Language: | en |
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McGill University
2006
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98778 |