Expression of the protein chaperone, clusterin, in spinal cord cells following cellular stress

Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease in which protein misfolding and aggregation are thought to play significant roles. Heat shock proteins (HSPs) bind misfolded proteins, regulate protein refolding or target misfolded proteins to the proteasome for degradat...

Full description

Bibliographic Details
Main Author: Zinkie, Samantha
Other Authors: Heather D Durham (Supervisor)
Format: Others
Language:en
Published: McGill University 2011
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97219