Investigation on the Effect of Menin on the TGF-b Pathway
TGF-β plays a dual role in cancer: In pre-malignant cells TGF-β inhibits tumor growth, but in malignant tumor cells it helps tumor progression. One of the most important effects of TGF-β is the induction of EMT, which allows epithelial cells to acquire mesenchymal traits, allowing tumors of epitheli...
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| Format: | Others |
| Language: | en |
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McGill University
2010
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95119 |