Predicting transcription factor binding sites using phylogenetic footprinting and a probabilistic framework for evolutionary turnover

Identifying genomic locations of transcription-factor binding sites (TFBS), particularly in higher eukaryotic genomes, has been an enormous challenge. Computational methods involving identification of sequence conservation between related genomes have been the most successful since sites found in su...

Full description

Bibliographic Details
Main Author: Parmar, Victor
Other Authors: Mathieu Blanchette (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2010
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=87000