Renal calcification in Npt2 knockout mice
Mice homozygous for the disrupted renal type 11a sodium/phosphate (Na/Pi) cotransporter gene, Npt2, (Npt2 KO) exhibit renal Pi wasting and hypercalciuria, predisposing factors for renal stone formation. We observed that Npt2 KO mice, but not wild-type littermates form renal stones. The renal sto...
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Format: | Others |
Language: | en |
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McGill University
2002
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=78338 |