Effects of folates and products of folate metabolism on proliferation of human leukemia cell line K562 in culture

Human leukemia cell K562 in culture displayed an absolute requirement for folate, proliferating at optimal rate only when the total intracellular folate concentration was greater than 1.5 uM. This critical intracellular concentration was maintained by extracellular 5-formyltetrahydrofolic acid or 5-...

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Bibliographic Details
Main Author: Watkins, David.
Format: Others
Language:en
Published: McGill University 1983
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=71903