Studies on molecular mechanisms of transformation by human papillomavirus : the role of E6 and E5 oncogenes
The ability of the HPV-18 E6 gene to impair p53-mediated transcriptional activity induced by DNA damaging agents was investigated. It is demonstrated that E6 can abolish DNA damage induced p53-mediated transcription and that a region from amino acid residue 113 to 117 of HPV-18 E6 protein was necess...
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| Format: | Others |
| Language: | en |
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McGill University
1996
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40133 |