Epigenetic crosstalk between DNA demethylation and histone acetylation

Abnormal methylation patterns such as regional hypermethylation and genomic hypomethylation often result in transcriptional changes of critical genes that are central to the progression of human cancers. It is therefore important to identify the mechanism...

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Bibliographic Details
Main Author: Ou, Jing Ni
Other Authors: Moshe Szyf (Supervisor)
Format: Others
Language:en
Published: McGill University 2009
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32413