Distinct roles of interferon regulatory factor (IRF)-3 and IRF-7 in the activation of the antitumor properties of human macrophages
The interferon (IFN) regulatory factors (IRF) are transcriptional mediators of the cellular innate immune defense. Two of these factors, IRF-3 and IRF-7, are the principal inducers of type I IFN (IFN-alpha and -beta), which are key players in the antiviral response. Type I IFNs also exert strong ant...
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| Format: | Others |
| Language: | en |
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McGill University
2008
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18752 |