Cellular organization of the netrin receptor DCC and its associated signaling pathways
The netrin-1 receptor Deleted in Colorectal Cancer (DCC) acts as a tyrosine kinase-associated receptor to mediate the attractive response of the growth cone towards the source of netrin-1. Fyn phosphorylates DCC on tyrosine 1418 to trigger neurite formation. DCC function requires lipid rafts, but it...
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| Format: | Others |
| Language: | en |
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McGill University
2008
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18667 |