Determining the role of the RNA-binding protein, RasGAP- SH3 domain-binding protein, in the mammalian cellular response to ultraviolet radiation
The RasGAP—SH3-domain Binding Protein (G3BP1) is an endoribonuclease that links Ras-signalling pathways and mRNA stability. Though implicated in many cellular roles, a well defined function for G3BP1 has yet to be determined. The aim of the following dissertation is to further implicate G3BP1 in mam...
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| Format: | Others |
| Language: | en |
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McGill University
2007
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18459 |