Characterization of the endogenous axin-based complexes and regulation in the Wnt pathway
Wnt-β-catenin signaling is a major pathway controlling gene transcription, cell cycle and cell fate determination. Deregulated Wnt signaling has been implicated in many human diseases, particularly cancers. The key step in the pathway seems to be the switch from constitutive degradation of β-catenin...
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| Format: | Others |
| Language: | en |
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McGill University
2014
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=123093 |