Allele-specific analyses of gene expression and chromatin state yield new insights into cis-regulatory mechanisms and their role in complex disease
Cis-regulatory variants are predicted to mediate the majority of the known common genetic associations to complex disease, yet the specific causal variants and the corresponding cis-regulatory mechanisms have thus far been poorly characterized. We attempted to address this by using allele-specific a...
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Language: | en |
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McGill University
2014
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121378 |