Role of protein-tyrosine phosphatase 1B in complement- mediated glomerular injury
Activation of endoplasmic reticulum (ER) stress, notably the unfolded protein response (UPR) and ER-associated degradation (ERAD), contributes to injury in certain renal glomerular diseases. Protein-tyrosine phosphatase 1B (PTP1B) was previously shown to enhance the IRE1α (inositol requiring-1α) bra...
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Format: | Others |
Language: | en |
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McGill University
2013
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119531 |