Role of protein-tyrosine phosphatase 1B in complement- mediated glomerular injury

Activation of endoplasmic reticulum (ER) stress, notably the unfolded protein response (UPR) and ER-associated degradation (ERAD), contributes to injury in certain renal glomerular diseases. Protein-tyrosine phosphatase 1B (PTP1B) was previously shown to enhance the IRE1α (inositol requiring-1α) bra...

Full description

Bibliographic Details
Main Author: Nezvitsky, Lisa
Other Authors: Andrey V E Cybulsky (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2013
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119531