Advancements in the synthesis of oligoribonucleotides on solid support and in solution: Ionic soluble supports, blockmer ribonucleotide amidites, and orthogonal linkers
This thesis is focused on the investigation of synthetic approaches for the preparation of oligonucleotides in solution. We describe our efforts to produce these valuable molecules in a more cost effective manner relative to the current industrial standards employing solid supported synthesis. We...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116981 |