The role of FOXP3 in human CD4+CD25+ regulatory T cell phenotype and function
Naturally occurring CD4+CD25High regulatory T cells (nTreg) have emerged as an essential component of self-tolerance. These cells arise in the thymus and represent 1-10% of CD4+ T cells in humans and mice. They constitutively express the FOXP3 transcription factor. The importance of FOXP3 for Treg c...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114261 |