Genomic mapping of single DNA molecules from Saccharomyces cerevisiae (brewer's yeast) by partial denaturation in nanochannels

Optical mapping of DNA provides large-scale genomic information that could be used to diagnose disease, detect pathogens, and study the re-arrangements between single cells crucial to the development of cancer. A recent optical mapping technique called denaturation mapping has the unique advantage o...

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Bibliographic Details
Main Author: Welch, Robert
Other Authors: Walter Reisner (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2012
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110725