Characterization of novel anti-EGFR single domain antibodies and their application in active targeting of superparamagnetic iron oxide nanoparticles to glioblastoma

Glioblastoma multiforme is the most lethal primary brain tumor with a mean patient survival of 12 - 15 months. Efforts to treat glioblastoma with chemotherapeutics or radiation therapy have been largely ineffective, which is why the current treatment paradigm is predominantly based on surgery. Herei...

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Bibliographic Details
Main Author: Trojahn, Ulrike
Other Authors: Arnim Pause (Supervisor2)
Format: Others
Language:en
Published: McGill University 2012
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107747