Comparing wild-type p53 and a p53 isoform, p47
p53 is a tumor suppressor protein that is mutated in over 50% of human cancers. Although tightly regulated under normal conditions, this protein is quickly activated in response to a multitude of cellular stresses, inducing several downstream pathways such as cell cycle arrest, apoptosis, and senesc...
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| Format: | Others |
| Language: | en |
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McGill University
2012
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107723 |