Characterization of met receptor tyrosine kinase-mediated endocytosis and its role in signal transduction and cellular migration

The Met receptor tyrosine kinase (RTK) and its ligand, hepatocyte growth factor (HGF) are potent regulators of epithelial remodeling, dispersal, and invasion and their deregulation is frequently observed in human cancers. These processes are coordinated through signal transduction pathways activated...

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Bibliographic Details
Main Author: Parachoniak, Christine
Other Authors: Morag Park (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2012
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106403