The study of allostery in aminoglycoside N-6'- acetyltransferase through the use of calorimetry and spectroscopy

Allostery is the change in structure, dynamics and/or function in biological macromolecules upon binding to a target molecule. Since its initial proposal, allostery has been shown to be essential to cellular function. One result of allostery is the cooperative binding of identical ligands to the s...

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Bibliographic Details
Main Author: Freiburger, Lee
Other Authors: Anthony Mittermaier (Internal/Cosupervisor2)
Format: Others
Language:en
Published: McGill University 2011
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104633