Allergen-induced growth of airway smooth muscle: structure-function relations and modulation by corticosteroids and the epidermal growth factor receptor
In experimental asthma, allergen challenges cause airway structural changes, termed remodeling, including an increase in smooth muscle (SM) mass and goblet cell metaplasia. These changes are substantially mediated via the epidermal growth factor receptor (EGFR) and its axis of ligands. The causal...
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Language: | en |
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McGill University
2011
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104472 |