Chemotherapy of candidiasis: study of ABC transporter- mediated azole resistance and identification of a novel antifungal therapeutic strategy

Candida albicans is a major fungal pathogen that causes systemic bloodstream infections with high mortality rate in immune-compromised patients. Current treatment of candidiasis involves the use of azoles (the most widely used antifungal agents that target ergosterol biosynthesis) and echinocandins...

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Bibliographic Details
Main Author: Tsao, Tan Ning
Other Authors: Bernard Turcotte (Internal/Cosupervisor2)
Format: Others
Language:en
Published: McGill University 2011
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103634