Chemotherapy of candidiasis: study of ABC transporter- mediated azole resistance and identification of a novel antifungal therapeutic strategy
Candida albicans is a major fungal pathogen that causes systemic bloodstream infections with high mortality rate in immune-compromised patients. Current treatment of candidiasis involves the use of azoles (the most widely used antifungal agents that target ergosterol biosynthesis) and echinocandins...
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Format: | Others |
Language: | en |
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McGill University
2011
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103634 |