Long double-stranded RNA-mediated suppression of PER2 in the SCN disrupts circadian locomotor activity and PER2 rhythms in the limbic forebrain

Long double-stranded RNA-mediated suppression of PER2 in the SCN disrupts circadian locomotor activity and PER2 rhythms in the limbic forebrain

Studies with targeted disruption in the Period2 ( Per2 ) gene suggest that the PER2 protein participates in the regulation of circadian behavioral rhythms. Moreover, it has been shown that direct suppression of PER2 expression in the suprachiasmatic nucleus (SCN) with antisense oligonucleotides disr...

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Bibliographic Details
Main Author: Gavrila, Alex M
Format: Others
Published: 2008
Online Access:http://spectrum.library.concordia.ca/975627/1/MR40828.pdf
Gavrila, Alex M <http://spectrum.library.concordia.ca/view/creators/Gavrila=3AAlex_M=3A=3A.html> (2008) Long double-stranded RNA-mediated suppression of PER2 in the SCN disrupts circadian locomotor activity and PER2 rhythms in the limbic forebrain. Masters thesis, Concordia University.

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http://spectrum.library.concordia.ca/975627/1/MR40828.pdf
Gavrila, Alex M <http://spectrum.library.concordia.ca/view/creators/Gavrila=3AAlex_M=3A=3A.html> (2008) Long double-stranded RNA-mediated suppression of PER2 in the SCN disrupts circadian locomotor activity and PER2 rhythms in the limbic forebrain. Masters thesis, Concordia University.

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