Probing the binding of interstrand crosslinked DNA containing a fluorescent base analog with human and E. coli homologs of O6-alkyl-guanine-DNA-alkyltransferase

Probing the binding of interstrand crosslinked DNA containing a fluorescent base analog with human and E. coli homologs of O6-alkyl-guanine-DNA-alkyltransferase

O6-alkylguanine-DNA-alkyltransferase (AGT) has been implicated in reducing the therapeutic efficacy of alkylating agents that cause mutations and apoptosis. Certain chemotherapeutic treatments involve the use of alkylating agents; bis-chloroethylnitrosourea (BCNU) is an example of an agent that has...

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Bibliographic Details
Main Author: Vergara, Jordan
Format: Others
Published: 2012
Online Access:http://spectrum.library.concordia.ca/975056/1/Vergara_MSc_S2013.pdf
Vergara, Jordan <http://spectrum.library.concordia.ca/view/creators/Vergara=3AJordan=3A=3A.html> (2012) Probing the binding of interstrand crosslinked DNA containing a fluorescent base analog with human and E. coli homologs of O6-alkyl-guanine-DNA-alkyltransferase. Masters thesis, Concordia University.

Internet

http://spectrum.library.concordia.ca/975056/1/Vergara_MSc_S2013.pdf
Vergara, Jordan <http://spectrum.library.concordia.ca/view/creators/Vergara=3AJordan=3A=3A.html> (2012) Probing the binding of interstrand crosslinked DNA containing a fluorescent base analog with human and E. coli homologs of O6-alkyl-guanine-DNA-alkyltransferase. Masters thesis, Concordia University.

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