Design, Characterization and Application of Amphipathic Peptides for siRNA Delivery

Design, Characterization and Application of Amphipathic Peptides for siRNA Delivery

Short interfering RNAs (siRNAs) are 21-23 nucleotide-long double-stranded RNA molecules that can trigger the RNA interference (RNAi). RNAi is a post-transcriptional gene silencing process whereby siRNAs induce the sequence-specific degradation of complementary messenger RNA (mRNA). Despite their pro...

Full description

Bibliographic Details
Main Author: Jafari, Mousa
Language:en
Published: 2013
Subjects:
RNAi
siRNA
peptide
physicochemical characterization
uptake mechanism
endocytosis
gene delivery
amphipathic
Online Access:http://hdl.handle.net/10012/7279

Internet

http://hdl.handle.net/10012/7279

Similar Items