Biochemical Investigations of L-Methionine gamma-lyase 1 from Trichomonas vaginalis

The enzyme L-methionine γ-lyase (MGL) utilizes a pyridoxal-5’-phosphate-cofactor in order to convert L-methionine to α-ketobutyrate, ammonia and methyl mercaptan. MGL is proposed to be a potential drug target since it is expressed in the human pathogens, Trichomonas vaginalis and Entamoeba histolyti...

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Bibliographic Details
Main Author: Moya, Ignace Adolfo
Language:en
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10012/6401