New Insights into the Regulation of Intestinal Immunity by Nod1 and Nod2

Nod1 and Nod2 are intracellular pattern recognition receptors that detect specific moieties of peptidoglycan, a critical component of the bacterial cell wall, to initiate host innate immune responses. Importantly, mutations in the human NOD2 gene have been associated with increased risk to develop m...

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Bibliographic Details
Main Author: Rubino, Stephen
Other Authors: Girardin, Stephen
Language:en_ca
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1807/44135