Tumour-stroma Signalling in Cancer Cell Motility and Metastasis

The tumour-associated stroma, consisting of fibroblasts, inflammatory cells, vasculature and extracellular matrix proteins, plays a critical role in tumour growth, but how it regulates cancer cell migration and metastasis is poorly understood. The Wnt-planar cell polarity (PCP) pathway regulates co...

Full description

Bibliographic Details
Main Author: Luga, Valbona
Other Authors: Wrana, Jeffrey
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/43634