Mechanical and Histological Characterization of Porcine Aortic Valves under Normal and Hypercholesterolemic Conditions

Mechanical and Histological Characterization of Porcine Aortic Valves under Normal and Hypercholesterolemic Conditions

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Calcific aortic valve disease (CAVD) is associated with significant cardiovascular morbidity. While late-stage valve disease is well-described, there remains an unmet scientific need to elucidate early pathobiological processes. In CAVD, pathological differentiation of valvular interstitial cells (V...

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Bibliographic Details
Main Author: Sider, Krista
Other Authors: Simmons, Craig Alexander
Language:en_ca
Published: 2012
Subjects:
heart valve
aortic valve disease
micromechanical testing
micropipette aspiration
multilayered biomaterial
histology
porcine
animal model
hypercholesterolemia
proteoglycan
lipid
Sox9
0541
Online Access:http://hdl.handle.net/1807/43395

Internet

http://hdl.handle.net/1807/43395

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