The Screening of Biomaterials to Support Long-term Growth and Maintenance of Human Embryonic Stem Cells in Xeno- and Feeder-free System

Current feeder-free culture systems employing undefined Matrigel are still more effective in maintaining human embryonic stem (ES) cells than defined surfaces using extracellular matrix (ECM) proteins. While the role of substrate stiffness in stem cell fate is becoming increasingly evident, all prev...

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Bibliographic Details
Main Author: Pang, Justin Tse Wei
Other Authors: Simmons, Craig Alexander
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/43297