Development of a Novel Imaging Methodology for Quantitative Analysis of the Mouse Cortical Vasculature

This thesis describes a novel imaging methodology for visualization and quantitative analysis of the vascular topology of different cortical regions of the mouse brain in 3D. The brain is perfused with a fluorescent contrast agent, and rendered fully transparent via optical clearing. This procedure...

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Bibliographic Details
Main Author: Steinman, Joe
Other Authors: Sled, John G.
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/42945