Modulation of Multidrug Resistance Phosphoglycoprotein in the Mouse Placenta and Fetal Brain by the Selective Serotonin Reuptake Inhibitor Sertraline and Maternal Bacterial Infection
Multidrug resistance phosphoglycoprotein (P-gp) is expressed in the placenta and fetal blood-brain barrier (BBB) and plays a critical role in reducing fetal accumulation of xenobiotics. In other tissues, P-gp activity is inhibited by selective serotonin reuptake inhibitors (SSRIs) and by lethal dose...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/42894 |