Regulation of Autophagy by Nlrp5 in Preimplantation Embryos
Previous studies have shown that NACHT, leucine rich repeat and PYD domain containing 5 (Nlrp5) deficient embryos fail to develop beyond the two-cell stage. Despite this strong phenotype, little is known of the function of NALP5 and the pathways affected by its deficiency. We showed that Nlrp5 defic...
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Language: | en_ca |
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2012
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Online Access: | http://hdl.handle.net/1807/42423 |