Regulation of Autophagy by Nlrp5 in Preimplantation Embryos

Previous studies have shown that NACHT, leucine rich repeat and PYD domain containing 5 (Nlrp5) deficient embryos fail to develop beyond the two-cell stage. Despite this strong phenotype, little is known of the function of NALP5 and the pathways affected by its deficiency. We showed that Nlrp5 defic...

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Bibliographic Details
Main Author: Naranian, Taline
Other Authors: Jurisicova, Andrea
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/42423