Investigation of ClpXP Protease Mechanism of Function and its Interaction with the Folding Chaperone Trigger Factor
The major chaperones identified in Escherichia coli that assist in protein folding include trigger factor (TF), DnaK/DnaJ/GrpE and GroEL/GroES systems. The main ATP-dependent proteases are ClpXP, ClpAP, HslUV, Lon, and FtsH. From detailed sequence analysis, we found that tig (gene for TF), clpX, and...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/36076 |