Trafficking of FcγRIIA and FcγRIIB2 upon Endocytosis of Immune Complexes

Fcγ receptors (FcγR) which recognize the Fc fraction of IgG play key roles in the modulation of a range of cellular responses as part of the host defense against foreign microbes and antigens. An important function of FcγR is to mediate internalization of soluble IgG-containing immune complexes via...

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Bibliographic Details
Main Author: Zhang, Christine
Other Authors: Booth, James
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/35753