The Role of Tim-3 Receptor in CD8+ T cells Cytotoxicity in Chronic HIV Infection
The Tim-3+ T cells in HIV infection are dysfunctional in proliferation or cytokine production. Here, we evaluated the effects of Tim-3 expression on the cytotoxicity of CD8+ T cells in HIV infection by examining 1) the ability of Tim-3+ CD8+ T cells to make perforin and 2) the direct ability of Tim-...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/35691 |