Investigating the Hippo Signaling Pathway using High-throughput Protein-protein Interaction LUMIER Screens
The Hippo pathway plays a key role in controlling organ growth and size. In mammals, core pathway components include the Lats1/2 and Mst1/2 kinases, which phosphorylate the transcriptional regulators, Taz and Yap. To identify novel upstream pathway regulators high throughput protein-protein interact...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/35681 |