Sex and Strain Differences in Acute Hepatotoxic and Inflammatory Responses to Liver Procarcinogens in the Developing Mouse

Sex and Strain Differences in Acute Hepatotoxic and Inflammatory Responses to Liver Procarcinogens in the Developing Mouse

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We previously observed that postnatal exposure of mice to the procarcinogen 4-aminobiphenyl (ABP) produced liver tumors only in wild-type males, while arylamine N-acetyltransferase deficient males and females of either strain were protected. Others have also observed a sex difference in liver tumors...

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Bibliographic Details
Main Author: Hanna, Daniel
Other Authors: Grant, Denis M.
Language:en_ca
Published: 2013
Subjects:
4-aminobiphenyl
Aromatic amines
Diethylnitrosamine
Carcinogenesis
Hepatocellular carcinoma
Hepatotoxicity
Inflammation
0419
0383
0433
0307
Online Access:http://hdl.handle.net/1807/35616

Internet

http://hdl.handle.net/1807/35616

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