The Development of Neurodegeneration and Behavioural Alterations following Lithium/Pilocarpine-induced Status Epilepticus in Rats
The lithium/pilocarpine model of epilepsy mimics mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) in humans. Systemic injection of pilocarpine in lithium chloride (LiCL) pretreated adult rats results in an acute episode of severe continuous seizure activity (status epilepticus, SE...
Main Author: | |
---|---|
Other Authors: | |
Language: | en_ca |
Published: |
2012
|
Subjects: | |
Online Access: | http://hdl.handle.net/1807/35162 |