The Development of Neurodegeneration and Behavioural Alterations following Lithium/Pilocarpine-induced Status Epilepticus in Rats

The lithium/pilocarpine model of epilepsy mimics mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) in humans. Systemic injection of pilocarpine in lithium chloride (LiCL) pretreated adult rats results in an acute episode of severe continuous seizure activity (status epilepticus, SE...

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Bibliographic Details
Main Author: Dykstra, Crystal
Other Authors: Milgram, Bill
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/35162