The Significance of the Evolutionary Relationship of Prion Proteins and ZIP Transporters in Health and Disease

The cellular prion protein (PrPC) is unique amongst mammalian proteins in that it not only has the capacity to aggregate (in the form of scrapie PrP; PrPSc) and cause neuronal degeneration, but can also act as an independent vector for the transmission of disease from one individual to another of th...

Full description

Bibliographic Details
Main Author: Ehsani, Sepehr
Other Authors: Schmitt-Ulms, Gerold
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33986