The Significance of the Evolutionary Relationship of Prion Proteins and ZIP Transporters in Health and Disease
The cellular prion protein (PrPC) is unique amongst mammalian proteins in that it not only has the capacity to aggregate (in the form of scrapie PrP; PrPSc) and cause neuronal degeneration, but can also act as an independent vector for the transmission of disease from one individual to another of th...
Main Author: | |
---|---|
Other Authors: | |
Language: | en_ca |
Published: |
2012
|
Subjects: | |
Online Access: | http://hdl.handle.net/1807/33986 |