Development of Novel Antiangiogenic Biologics
Current anti-VEGF biologics, such as bevacizumab and VEGF trap, have been successfully used as therapeutic agents for cancer and age-related macular degeneration (AMD). Since these strategies target VEGF systemically, their toxicity profile, including proteinuria and thromboembolic events, and need...
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Language: | en_ca |
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2012
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Online Access: | http://hdl.handle.net/1807/33856 |