Development of Novel Antiangiogenic Biologics

Current anti-VEGF biologics, such as bevacizumab and VEGF trap, have been successfully used as therapeutic agents for cancer and age-related macular degeneration (AMD). Since these strategies target VEGF systemically, their toxicity profile, including proteinuria and thromboembolic events, and need...

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Bibliographic Details
Main Author: Michael, Iacovos
Other Authors: Nagy, Andras
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33856