A Novel Approach for Identifying Synthetic Dosage Lethal Interactions in Pooled Yeast Cultures
Systematic genomic studies in the budding yeast S. cerevisiae have greatly increased our capacity to conduct functional profiling of the eukaryotic genome. I describe a new method that makes use of yeast “Barcoder” strains to uniquely tag strains in a yeast overexpression collection (FLEX) and to sy...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33726 |